Culture Otaku
Voice actress Ayane Sakura reveals the severe illness that nearly ruined her life
The voice of Yotsuba Nakano in The Quintessential Quintuplets overcame a rare illness and bullying before debuting.
Behind the cheerful and charismatic tone of characters that marked a whole generation, lie stories of overcoming that show how tough life can be before finding a purpose. The renowned seiyuu Ayane Sakura surprised her followers by sharing unprecedented details about her childhood and adolescence, revealing how a strange medical condition and social isolation nearly ruined her future.

It all began when she was just in fifth grade. During a minibasketball training session in the summer, Sakura fainted and fell to the ground unresponsive. Upon regaining consciousness, she discovered with distress that her legs wouldnβt respond and standing up was practically impossible. After several tests, doctors diagnosed her with orthostatic dysregulation and an autonomic nervous system disorder, conditions that were little known at the time and left the young girl confused about what was happening to her body.
To make matters worse, her situation worsened after a new classmate cruelly rejected her tastes and interests, delivering a devastating emotional blow. The combination of physical pain and this rejection led her to retreat home and repeatedly skip classes for years. With her father working abroad and her mother working all day, she spent long days alone blaming herself for not being an ordinary girl. However, amid loneliness, a teacher offered her a hand with admirable patience: instead of pressuring her to return to class, he visited her to play cards and share chocolates, a small gesture of empathy that ultimately changed her perspective on life.

In middle school, Sakura decided to join a theater company seeking an escape from her problems. Although she soon realized that acting on stage wasnβt her strength, a voice instructor noticed the unique tone of her vocal cords and suggested she try her luck in voice acting. Convinced to give it a try, she entered a specialized academy and achieved her professional debut while still in high school. Surprisingly, despite her absences from traditional school, she never missed a single voice acting class.
Established as one of the most important voice actresses in Japanβs industry, Ayane Sakura has lent her voice to iconic pop culture characters such as Ochako Uraraka in My Hero Academia and Yotsuba Nakano in The Quintessential Quintuplets. Her impeccable career demonstrates how resilience and proper support in the darkest moments can completely transform a personβs destiny.
Knowing the tough battle Ayane Sakura faced during her youth, did you imagine that behind the voices of cheerful characters like Ochako or Yotsuba there was such a profound story of overcoming?
No one trusted Yani Neko but the smoking cat girl ended up dominating

